It is currently difficult for physicians to detect small tumors and the precise boundaries of tumors during surgery. Fluorescent probes have improved tumor visualization, but these probes typically have high background signal or requires hours to illuminate. Recently, Kobayashi and colleagues developed a fluorescence probe- γ-glutamyl hydroxymethyl rhodamine green- that rapidly turns fluorescent green when it interacts with cancer cells, but not normal tissue (specifically when γ-glutamyltranspeptidase on the surface of cancer cells cleaves glutamate off the probe). When the probe is sprayed onto an in vivo mouse model of ovarian cancer, the probe activates within 1 minute, illuminating tumors <1 mm in diameter.
Movie: The hydroxymethyl rhodamine green probe is sprayed on a peritoneally disseminated SHIN3 ovarian cancer in a mouse. The movie was obtained with a regular camcorder.
Ladies, watch this video its only like 3 minutes long but i feel like a changed person.
This is kind of a wonderful video (and brief!) that I think will really impact and resonate with women of all ages. Dudes, this is still pretty relevant to you, as well! Love yourself, love others - Isn’t that the goal?